High severity · published Sep 27, 2026
CVE-2026-100843
MONAI before 1.6.0 Remote Code Execution via algo_from_pickle
7.8
CVSS
0.3%
EPSS
No
On KEV
Description
MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.
CVSS vector
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
Attack vector
Local
Complexity
Low
Privileges
None
User interaction
Required
Confidentiality
High
Integrity
High
Availability
High
Scope
Unchanged
Exploitation
Is it being used?
Exploit prediction (EPSS)0.3% · higher than 23% of CVEs
Exploited in the wildNo evidence yet
CISA KEVNot listed
Ransomware campaign useNot known
Affected products
Which versions
MO
MONAI · Project-MONAI
before 1.6.0 · source: vendor, NVD
References
NVD
https://nvd.nist.gov/vuln/detail/CVE-2026-100843
CVE.org
https://www.cve.org/CVERecord?id=CVE-2026-100843
vendor-advisory
https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-qxq5-qhx6-94qw
third-party-advisory
https://www.vulncheck.com/advisories/monai-before-1.6.0-remote-code-execution-via-algo-from-pickle
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